What Is Intermittent Explosive Disorder? Symptoms & Treatments – Joanne Martelli, PMHNP-BC

You’ve been there—the sudden flood of heat to your face, the seething white-hot anger over something trivial, the words or deeds that burst out before you can catch them. Afterwards, you’re left with regret, bewilderment, and the overwhelming idea: “Why can’t I control this?” If this rings a bell, you may be experiencing intermittent explosive disorder (IED), a condition that impacts 1 in 20 adults. In contrast to daily frustration, IED entails sudden, out-of-proportion explosions that destroy relationships, careers, and self-esteem.

The scary aspect? Even most with IED have no idea that it is a treatable condition, not a character flaw. “Patients often tell me, ‘I thought I was a bad person,'” says Joanne Martelli, PMHNP-BC. “But IED is a matter of brain chemistry, not character.” Let’s dissect what IED actually looks like, why it occurs, and—most importantly—how to take back control.

1. Overview: What Is Intermittent Explosive Disorder?

Intermittent explosive disorder (IED) is a psychiatric disorder where there are repeated fits of anger or aggression that are out of proportion to the provoking event. The outbursts can vary from verbal outbursts—yelling or threatening—to physical aggression or destruction of property. Between episodes, individuals tend to be appropriately behaved and, following an outburst, may express extreme regret.

IED vs “Normal” Anger: What’s the Difference

We all lose our cool occasionally, but IED symptoms are on a whole other level. Picture yelling at a barista for getting an order wrong, tossing your laptop in the middle of a meeting with coworkers, or physically attacking a loved one—all followed by overwhelming shame.

2. IED Disorder Symptoms & Presentation

Key IED disorder symptoms include:

  • Impulsive aggression: Sudden, unplanned outbursts of verbal or physical aggression.
  • Disproportionate response: Anger far exceeds any real threat posed by the trigger.
  • Short duration: Episodes peak quickly and resolve within 30 minutes.
  • Post-episode remorse: Feelings of shame, regret, or embarrassment follow the outburst.
  • Physical signs: Racing heart, chest tightness, tremors preceding or during attacks.

Between attacks, people often return to their baseline behavior, separating IED from other mood or psychotic diseases. According to a 2023 Cleveland Clinic study, 80% of persons with IEDs suffer from anxiety, depression, or substance abuse, with many turning to drink or drugs to numb the guilt between outbursts.

3. Prevalence & Who’s Affected

  • Lifetime prevalence: Estimated that 4–7% of U.S. adults experience IED at some point.
  • 12-month prevalence: Approximately 3.9% report IED in a given year.
  • Demographics: More common in males and often first appears in late childhood or adolescence, persisting into adulthood.
  • Comorbidity: Up to 80% of individuals with IED have another mental disorder, typically anxiety, mood disorders, or substance use disorders.

4. Causes & Risk Factors

While the precise cause of intermittent explosive disorder remains under study, research points to:

  • Genetics: Family history accounts for 44–72% of the risk for impulsive aggression.
  • Biological factors: Altered brain structure/function—especially reduced amygdala regulation—and low serotonin levels correlate with IED.
  • Environmental influences: Childhood trauma, abuse, or witnessing violence increases IED risk.

These components interact to reduce the inhibitory threshold for aggressive impulses, so minor frustrations appear able to trigger explosive outbursts.

5. Diagnosis: DSM-5 Criteria

In order to qualify for DSM-5 intermittent explosive disorder, one must exhibit recurrent behavioral outbursts indicating a lack of aggressive impulse control, evidenced by either:

  1. High frequency/low intensity: Verbal or low-level physical aggression toward people, animals, or property ≥2 times/week over three months, with no significant harm.
  2. Low frequency/high intensity: ≥3 episodes/year involving damage or physical assault causing harm.

Also, the outbursts must be impulsive, out of proportion, and not better described by another medical or mental condition.

6. Intermittent Explosive Disorder Treatment

6.1 Psychotherapy (CBT & Group Therapy)

Cognitive Behavioral Therapy (CBT) is the cornerstone of anger disorder treatment for IED:

  • Efficacy: In a randomized trial, 12-week CBT significantly lowered aggression scores compared with waitlist controls.
  • Techniques:
    • Cognitive restructuring to challenge harmful beliefs about provocation.
    • Relaxation training (deep breathing, progressive muscle relaxation) to reduce physiological arousal.
    • Coping skills via role-play and relapse prevention.

Group CBT further enhances outcomes, offering peer support and skill modeling.

6.2 Medications

Although no drug is FDA-approved for IED alone, a number of classes can increase the threshold for aggression:

  • SSRIs (e.g., fluoxetine): A double-blind study had a 46% remission rate of IED symptoms at endpoint with fluoxetine compared to placebo.
  • Mood stabilizers/anticonvulsants (divalproex, carbamazepine, phenytoin, lithium): Trials indicate these decrease aggressive outbursts, but findings are variable and additional trials are required.
  • Antipsychotics and anxiolytics: Occasionally used adjunctively for the acute management of aggression.

Medication selection is individualized, weighing effectiveness against side effects.

7. Self-Help & Lifestyle Strategies

In addition to professional care, daily practices support anger disorder treatment:

  • Stress management: Regular exercise and relaxation techniques lower baseline irritability.
  • Sleep hygiene: Consistent sleep restores emotional regulation.
  • Substance avoidance: Alcohol and stimulants worsen impulsivity.
  • Support networks: Family education and support groups reduce isolation and provide accountability.

8. Outlook, Prognosis, and Prevention

  • Prognosis: With sustained therapy and/or medication, individuals often see dramatic reductions in the frequency and severity of outbursts.
  • Chronic nature: IED can persist for 12–20+ years, requiring long-term management.
  • Prevention: Prompt intervention, particularly following traumatic experiences, can reduce progression. Instruction in coping mechanisms in high-risk adolescents can decrease later IED onset.

9. Conclusion & Next Steps

Intermittent explosive disorder can feel like you can’t stop it, but it is a legitimate mental illness with definite diagnostic criteria and helpful treatments. If you or someone close to you has sudden, out-of-proportion bursts of anger, especially if they damage relationships or safety, keep the following steps in mind:

  1. Seek an evaluation from a psychiatrist, psychologist, or PMHNP-BC.
  2. Ask about CBT programs tailored for IED.
  3. Discuss medication options like fluoxetine or mood stabilizers.
  4. Implement self-help strategies daily to build resilience.

With dedication to treatment and support, individuals with IED can take control, minimize harm, and achieve more balanced lives. Ready to get help from a professional? Joanne’s practice provides treatment for IED that is developed based on your triggers and your life. Call (623) 692-9933 or come see her in Chandler, AZ. Because you deserve landmine-free relationships—and a mind that feels like home.